Havzaho yo markazhoi adabi. Odamon dar hama holatho ruyi niyoz ba ilm, farhang va adab ovardaand. Dar asri XVI, sarfi nazar az nooromihoi siyosi, dar qalamravi Osiyoi Miyona, Eron, Hinduston markazhoi ilmi, farhangi va adabi faoliyat kardaand, ki dar rushdi jomeavu farhang naqshi muhim guzoshtaand: dar Osiyoi Miyona – Samarqand, Bukhoro, Badakhshon; dar sarzamini Eron – Isfahonu Mashhad, SHeroz, Tabrez; dar mulki Hind – Dehli, Multon, Lohur, Panjob, Kashmir, Sarhind. Har kadome az in doirahoi farhangiyu adabi dar peshrafti sohahoi mazkur naqshi sazovor guzoshtaand. Masalan, dar Osiyoi Miyona: Mushfiqi, Nisori, Mutribi, SHavkati Bukhoroi Samandarkhojai Tirmizi, Mulhami Bukhoroi, Fitrati Zarduz, Sayyido va digaron; dar Eron: Soibi Tabrezi, Kalimi Koshoni, Urfii SHerozi, Mirzo Muhammadtohiri Nasrobodi va digaron; dar Hinduston: Fayzii Dakani, Bedili Dehlavi va gayra.
Boyad guft, ki avzoi farhangu adabiyot dar nimai avvali asri XVI nisbat ba nimai duyum khele farqkunanda ast. Hamlai SHoh Ismoili Safavi soli 1512 ba Huroson, boisi parokandagii quvvahoi ilmiyu adabi gardid. Beshtar quvvahoi adabi ru ba Movarounnahr ovardand. Vosifi dar «Badoe-ul-vaqoe» khabar medihad, ki: «Dar on vaqt (soli1512) qarib panjsad kas az viloyati Huroson azimati mulki Movarounnahr kardand».
Dar in sarzamin ilmhoi tarikh, falsafa, riyoziyot, handasa, zabonu adabiyot, mantiq, musiqi khele pesh raftaast. Masalan, Muhammadsolehi Karminagi dar ilmi mantiq, Mavlono Kavkabii Bukhoroi dar nujumu musiqi, Ismatullohi Samarqandi dar sarfu nahv, Hoja Kaloni Samarqandi dar hakmatu riyoziyot az jumlai saromadoni asri khud budand.
Ilmi musiqi yake az dastovardhoi khalqi tojik dar asri XVI buda, dar se shahr: Hirot, Samarqand va Bukhoro khele pesh raftaast. Dar in bora Hofizi Tanish («SHarafnomai shohi»), Darveshalii CHangi («Tuhfat-us-surur»), Said SHarifi Samarqandi («Tarikhi kasira») az simohoi mashhuri asr: Bobojoni Hofiz, Dustmuhammadi Udi, Muhammadalii Noi, Ahmadi Hofiz, Ibni CHangi va digaron yod kardaand.
Tarikhnavisi niz khele pesh raftavu asarhoi garonarzishe ba maydon omadaand. Az jumla «Ravzat-us-safo»-i Mirkhond, «Habib-us-siyar»-i Hondmir, «SHayboninoma» va «Futuhoti khoni»-i Binoi» «Muntakhab-ut-tavorikh»-i Hofizi Ubahi, «SHa- rafnomai shohi» yo «Abdullohnoma»-i Hofizi Tanish va gayra mahsuli hamin asrand.